A COX-2 inhibitor

Celecoxib is available from Abcam as ab141988.
Catalog #: 1574 | abID:

Product Details

Alternate Name Celebrex, Celebra, Celecox, SC-58635
Appearance Off-white solid
CAS # 169590-42-5
Molecular Formula C₁₇H₁₄F₃N₃O₂S
Molecular Weight 381.37
Purity ≥99%
Solubility DMSO (200 mg/ml) or EtOH (100 mg/ml)
InChi InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
PubChem CID 2662
MDL Number MFCD00941298
Handling Protect from light and air
Storage Conditions -20°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


Celecoxib is a highly selective COX-2 inhibitor and primarily inhibits prostaglandin production. Celecoxib is approximately 7.6-fold more selective for COX-2 inhibition over COX-1. This specificity allows celecoxib to reduce inflammation and pain while minimizing gastrointestinal adverse drug reactions that are common with non-selective non-steroidal anti-inflammatory drugs.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.
Mao et al., Melanoma-Educated CD14+ Cells Acquire a Myeloid-Derived Suppressor Cell Phenotype through COX-2–Dependent Mechanisms. Cancer Res., Jul 2013; 73: 3877 - 3887.
Natasa Obermajer et al., Induction and stability of human Th17 cells require endogenous NOS2 and cGMP-dependent NO signaling. J. Exp. Med., Jun 2013; 210: 1433 - 1445.
Natasa Obermajer, et. al. Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells. Blood, Nov 2011; 118: 5498 - 5505.
Fujita, M. et. al. COX-2 Blockade Suppresses Gliomagenesis by Inhibiting Myeloid-Derived Suppressor Cells. Cancer Res., Apr 2011; 71: 2664 - 2674.
Lee, H. et al. Generation of regulatory dendritic cells and CD4+Foxp3+ T cells by probiotics administration suppresses immune disorders PNAS, Feb 2010; 107: 2159 - 2164.
For more citations of this product click here