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CD79B, human recombinant

Required for BCR-mediated signaling
Catalog #: 7318
$290.00

Product Details

Cat # +Size 7318-50
Size 50 μg
Alternate Name CD79b molecule, immunoglobulin-associated beta, AGM6, B29, IGB
Gene Symbol CD79B
Gene ID 974
Accession # P40259
Source E. coli
Appearance Liquid
Physical Form Description 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea and 10% glycerol.
Molecular Weight 17.7 kDa (155 aa, 29-159 aa + His tag), confirmed by MALDI-TOF.
Purity by SDS-PAGE ≥90%
Endotoxin Level < 1.0 EU per 1 microgram of protein
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMARSEDR YRNPKGSACS RIWQSPRFIA RKRGFTVKMH CYMNSASGNV SWLWKQEMDE NPQQLKLEKG RMEESQNESL ATLTIQGIRF EDNGIYFCQQ KCNNTSEVYQ GCGTELRVMG FSTLAQLKQR NTLKD
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

CD79B, also known as Igb and B29, is a 36 kDa transmembrane glycoprotein in the immunoglobulin superfamily. Heterodimers of CD79A and CD79B associate with a membrane bound immunoglobulin on the B cell surface to form the B cell antigen receptor complex (BCR). CD79A and CD79B are required for BCR-mediated signaling and consequently for the development and activation of B lineage cells. Recombinant human CD79B protein, fused to His-tag at N-terminus, was expressed in E.coli.


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