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CD58 Antibody

Polyclonal Antibody to detect CD58 in human, mouse and rat samples.
Catalog #: 6939
$190.00

Product Details

Cat # +Size 6939-50
Size 50 µl
Antibody Target CD58
Alternate Name LFA3; Lymphocyte function-associated antigen 3; Ag3; Surface glycoprotein LFA-3; CD58
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen This CD58 antibody is generated from KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD58. The exact sequence is proprietary.
Accession # P19256
Gene ID 965
Appearance Colorless liquid
Concentration 1 mg/ml
Formulation 1 mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification Immunogen Affinity chromatography
Species Reactivity Human, Mouse, Rat
Application WB
Positive Control WB: HEK293T, Raw264.7, H9C2 whole cell lysates
Application & Usage WB: 1:500 - 1:1000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of its cognate ligand, CD2, on the T cell surface.


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