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CD4 Antibody

Polyclonal Antibody to detect CD4 in human, mouse, dog, monkey and rat samples.
Catalog #: 6937
$190.00

Product Details

Cat # +Size 6937-50
Size 50 µl
Antibody Target CD4
Alternate Name T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; CD4
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen This CD4 antibody is generated from KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD4. The exact sequence is proprietary.
Accession # P01730
Gene ID 920
Appearance Colorless liquid
Concentration 1 mg/ml
Formulation 1 mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification Immunogen Affinity chromatography
Species Reactivity Human, Mouse, Rat, Dog, Monkey
Application WB
Positive Control WB: SP20, PC12, H9C2 whole cell lysate
Application & Usage WB: 1:500 - 1:1000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CD4 is a cell-surface glycoprotein found on the mature helper T cells and immature thymocytes, as well as on monocytes and macrophages. (Some cytotoxic T cells have CD4 protein as well.) Normally, about 65% of T cells in the blood are CD4+ (have CD4 protein protruding from their membrane). A mature T cell with have either CD4 or CD8, but not both. During one stage of development T cells develop CD4 and CD8 receptors, but they eventually are differentiated in the thymus and become more specialized. CD4 is also expressed on cortical cells, mature medullary thymocytes, microglial cells and dendritic cells.


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