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CD3G, human recombinant

Plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways
Catalog #: 7313

In stock

$295.00

Product Details

Cat # +Size 7313-100
Size 100 μg
Alternate Name CD3g molecule, gamma (CD3-TCR complex), CD3-GAMMA, T3G
Gene Symbol CD3G
Gene ID 917
Accession # P09693
Source E. coli
Appearance Liquid
Physical Form Description 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.
Molecular Weight 13.1 kDa (117 aa, 23-116 aa + His tag), confirmed by MALDI-TOF.
Purity by SDS-PAGE ≥90%
Endotoxin Level < 1.0 EU per 1 microgram of protein
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSQSIKGNH LVKVYDYQED GSVLLTCDAE AKNITWFKDG KMIGFLTEDK KKWNLGSNAK DPRGMYQCKG SQNKSKPLQV YYRMCQNCIE LNAATIS
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. Recombinant human CD3G protein, fused to His-tag at N-terminus, was expressed in E.coli.


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