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CD274, mouse recombinant

Involved in the costimulatory signal, essential for T-cell proliferation
Catalog #: 7311
$295.00

Product Details

Cat # +Size 7311-100
Size 100 μg
Alternate Name CD274 antigen, A530045L16Rik, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Gene Symbol CD274
Gene ID 60533
Accession # Q9EP73
Source E. coli
Appearance Liquid
Physical Form Description 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl and 10% glycerol.
Molecular Weight 27.6 kDa (246 aa, 19-239 aa + His tag), confirmed by MALDI-TOF.
Purity by SDS-PAGE ≥85%
Endotoxin Level < 1.0 EU per 1 microgram of protein
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSHM RASLPKDQLL KGNAALQITD VKLQDAGVYC CIISYGGADY KRITLKVNAP YRKINQRISV DPATSEHELI CQAEGYPEAE VIWTNSDHQP FTITA PKDLYVVEYG SNVTMECRFP VERELDLLAL VVYWEKEDEQ VIQFVAGEED LKPQHSNFRG VSGKRSVTTS RTEGMLLNVT SSLRVNATAN DVFYCTFWRS QPGQNHTAEL I
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

CD274, also known as programmed cell death 1 ligand 1(PDCD1L1), is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. This protein interacts with PDCD1 inhibits T-cell proliferation and cytokine production. Recombinant mouse CD274 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.


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