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Anti-CD27 Antibody

Polyclonal antibody to detect CD160 in human samples.
Catalog #: A1074
$155.00

Product Details

Cat # +Size A1074-100
Size 100 µg
Antibody Target CD27
Alternate Name CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD27, CD27, TNFRSF7
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen KLH conjugated synthetic peptide between 196-225 amino acids from the C-terminal region of human CD27.
Accession # P26842
Gene ID 939
Appearance Colorless liquid
Formulation PBS with 0.09% (W/V) sodium azide.
Purification Protein A column, followed by peptide affinity purification.
Species Reactivity Human
Application WB, FC
Positive Control FC
Application & Usage WB~~1:1000FC~~1:10~50
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.


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