Product Details
| Cat # +Size | A1073-100 |
|---|---|
| Size | 100 µg |
| Antibody Target | CD244 |
| Alternate Name | Natural killer cell receptor 2B4, NK cell activation-inducing ligand, NAIL, NK cell type I receptor protein 2B4, NKR2B4, h2B4, SLAM family member 4, SLAMF4, Signaling lymphocytic activation molecule 4, CD244, CD244, 2B4 |
| Host | Mouse |
| Antibody Type | Monoclonal |
| Isotype | Mouse IgG1, kappa light chain |
| Immunogen | CD244 Fusion protein |
| Accession # | Q9BZW8 |
| Gene ID | 51744 |
| Appearance | Colorless liquid |
| Formulation | Supplied in PBS with < 0.1% sodium azide and 0.1% gelatin |
| Species Reactivity | Human |
| Application | Western blot, FC, IP |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | Store at 4 °C in small working aliquots. DO NOT FREEZE. |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Mouse anti-Human CD244 antibody, clone 2B4.69 recognizes the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4). CD244 is a 370 amino acid single pass type I transmembrane glycoprotein with two Ig-like V type domains. CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells.CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of CD244 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.
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