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Anti-CD244 Antibody (2B4.69)

Monoclonal antibody to detect CD276 in human samples.
Catalog #: A1073
$345.00

Product Details

Cat # +Size A1073-100
Size 100 µg
Antibody Target CD244
Alternate Name Natural killer cell receptor 2B4, NK cell activation-inducing ligand, NAIL, NK cell type I receptor protein 2B4, NKR2B4, h2B4, SLAM family member 4, SLAMF4, Signaling lymphocytic activation molecule 4, CD244, CD244, 2B4
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG1
Immunogen CD244 Fusion protein
Accession # Q9BZW8
Gene ID 51744
Appearance Colorless liquid
Formulation PBS with 0.09% (W/V) sodium azide.
Purification Protein A column, followed by peptide affinity purification.
Species Reactivity Human
Application FC, IP
Positive Control FC
Application & Usage FC, IP
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Mouse anti-Human CD244 antibody, clone 2B4.69 recognizes the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4). CD244 is a 370 amino acid single pass type I transmembrane glycoprotein with two Ig-like V type domains. CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells.CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of CD244 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.


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