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CD244, human recombinant

Aids in eosinophil adhesion and chemotaxis
Catalog #: 7339
$295.00

Product Details

Cat # +Size 7339-50
Size 50 μg
Alternate Name CD244 molecule, natural killer cell receptor 2B4, 2B4, NAIL, NKR2B4, Nmrk, SLAMF4
Gene Symbol CD244
Gene ID 51744
Accession # Q9BZW8
Source E. coli
Appearance Liquid
Physical Form Description 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea.
Molecular Weight 25.5 kDa (230 aa, 19-224 aa + His Tag), confirmed by MALDI-TOF.
Purity by SDS-PAGE ≥85%
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSH GKGCQG SADHVVSISG VPLQLQPNSI QTKVDSIAWK KLLPSQNGFH HILKWENGSL PSNTSNDRFS FIVKNLSLLI KAAQQQDSGL YCLEVTSISG KVQTATFQVF VFDKVEKPRL QGQGKILDRG RCQVALSCLV SRDGNVSYAW YRGSKLIQTA GNLTYLDEEV DINGTHTYTC NVSNPVSWES HTLNLTQDCQ NAHQEFRFWP
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

CD244 (Natural Killer Cell Receptor 2B4), also known as Cluster of Differentiation 244, contains 2 Ig-like (immunoglobulin-like) domains. A role for the subtypes of CD2 Ig superfamily receptors has been recently demonstrated in eosinophilic inflammation in experimental asthma and atopic asthmatics. Functions of CD244 molecules are in eosinophil adhesion and chemotaxis, and correlated the results to the pathophysiology of allergic rhinitis (AR). The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Recombinant human CD244 protein, fused to His-tag at N-terminus, was expressed in E.coli.


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