Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

CD-14, human recombinant

A high affinity receptor for complexes of LPS and LPS binding protein
Catalog #: 4937

Product Details

Cat # +Size 4937-10
Size 10 μg
Alternate Name CD14, Cluster of differentiation 14, Human CD14, CD14, h-CD14, rh-CD14, recombinant human CD14, recombinant CD14, CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein
Gene Symbol CD14
Gene ID 929
Accession # P08571
Source CHO cells
Appearance Lyophilized protein
Physical Form Description Lyophilized from a concentrated protein solution (1 mg/ml) containing PBS, pH 7.2
Molecular Weight 50.0 kDa
Purity by SDS-PAGE 90-95%
Endotoxin Level <0.1 ng/μg
Biological Activity Inhibits binding of LPS to CD14. Upto to 20 µg/ml CD14 inhibit binding of FITC-LPS (0.5µg/ml) to 6 x 105 CD14+CHO transfectants (FACS)
Reconstitution Instructions Reconstitute in 10 µl of ultra-pure distilled water. This solution can then be diluted into other aqueous buffers and stored at –20°C or –70°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans


CD14 acts as a receptor for endotoxin (LPS), is expressed strongly on monocy¬tes, macro¬pha¬ges and weekly at surface of neutrophiles. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor LPS-LBP (lipopolysaccharide binding protein)-complexes. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids, acts at physiological concentrations as LPS agonist and has at higher concentrations an antagonizing effect in cell activation. The myeloid differentiation antigen CD14 acts as the major receptor for bacterial LPS. The dominant form of the recombinant wild type CD14 is the 50 kDa protein.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.