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CCT128930

A potent, selective, novel and ATP-competitive inhibitor for AKT2
Catalog #: B1763

In stock

SKU-Size Size Price Qty
B1763-1 1 mg
$125.00
B1763-5 5 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name CCT128930; CCT 128930; CCT-128930; 4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-amine; 4-[(4-chlorophenyl)methyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-amine
Appearance Solid
CAS # 885499-61-6
Molecular Formula C₁₈H₂₀ClN₅
Molecular Weight 341.84
Purity >98%
Solubility DMSO
SMILES C1CN(CCC1(CC2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4
InChi InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23)
InChi Key RZIDZIGAXXNODG-UHFFFAOYSA-N
PubChem CID 17751819
MDL Number MFCD13177916
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CCT128930 is a potent, selective, novel and ATP-competitive inhibitor for AKT2 (IC50= 6 nM). It also has 28-fold and 20-fold selectivity over PKA kinase (IC50= 168 nM) and p70S6K (IC50= 120 nM), respectively.


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