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Product Details
| Cat # +Size | 7305-100 |
|---|---|
| Size | 100 μg |
| Alternate Name | C-C motif chemokine 3-like 1, CCL3L3, D17S1718, G0S19-2, LD78, LD78BETA, MIP1AP, SCYA3L; SCYA3L1 |
| Gene Symbol | CCL3L1 |
| Gene ID | 6349 |
| Accession # | P16619 |
| Source | E. coli |
| Appearance | Liquid |
| Physical Form Description | 0.25 mg/ml in Phosphate Buffered Saline pH 7.4 containing 10% glycerol |
| Molecular Weight | 10 kDa (90 aa, 26-93 aa + His tag), confirmed by MALDI-TOF. |
| Purity by SDS-PAGE | ≥90% |
| Endotoxin Level | < 1.0 EU per 1 microgram of protein |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MSLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -80°C |
| Shipping Conditions | Dry Ice |
| USAGE | For Research Use Only! Not to be used in humans |
Details
CCL3L1 is a small cytokine belonging to the CC chemokine. This protein is involved in immunoregulatory and inflammatory processes. It binds to several chemokine receptors including chemokine binding protein 2 (CCBP2 or D6) and chemokine (C-C motif) receptor 5 (CCR5). Recombinant human CCL3L1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
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