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CCL21, human recombinant

Inhibits hemopoiesis and stimulates chemotaxis
Catalog #: 7338
$375.00

Product Details

Cat # +Size 7338-50
Size 50 μg
Alternate Name C-C motif chemokine 21, 6Ckine, CKb9, ECL, SCYA21, SLC, TCA4.
Gene Symbol CCL21
Gene ID 6366
Accession # O00585 
Source E. coli
Appearance Liquid
Physical Form Description 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, and 1 mM DTT.
Molecular Weight 14.5 kDa (132 aa, 24-134 aa + His Tag), confirmed by MALDI-TOF.
Purity by SDS-PAGE ≥90%
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSDGGAQDCC LKYSQRKIPA KVVRSYRKQE PSLGCSIPAI LFLPRKRSQA ELCADPKELW VQQLMQHLDK TPSPQKPAQG CRKDRGASKT GKKGKGSKGC KRTERSQTPK GP
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

CCL21 is member of the chemokine superfamily and the subfamily of CC chemokines that has an aspartate cysteine-cysteine-leucine motif near its amino-terminus. This protein is involved in inhibits hemopoiesis and stimulates chemotaxis. CCL21 is chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. It may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. Recombinant CCL21 protein was expressed in E.coli and purified by using conventional chromatography techniques.


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