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CCL14/HCC-1/HCC-3, human recombinant

Activator of monocytes
Catalog #: 4275
SKU-Size Size Price Qty
4275-10 10 μg
$165.00
4275-50 50 μg
$475.00
4275-1000 1 mg
$3,570.00
More Sizes Get Quote

Product Details

Alternate Name C-C motif chemokine 14, Chemokine CC-1/CC-3, HCC-1/HCC-3, HCC-1(1-74), NCC-2, Small-inducible cytokine A14, Cleaved into: HCC-1(3-74), HCC-1(4-74), HCC-1(9-74)
Gene Symbol CCL14
Gene ID 6358
Accession # Q16627
Source Mammalian cell expression system
Appearance Lyophilized protein
Physical Form Description Lyophilized from a 0.2 μm filtered solution of 20 mM PB and 150 mM NaCl, pH 7.2.
Molecular Weight ~9.5 kDa
Purity by SDS-PAGE ≥95%
Purity by ≥95%
Endotoxin Level <0.1 ng/μg (1 IEU/μg)
Reconstitution Instructions Dissolve in 1x PBS (It is not recommended to reconstitute to a final concentration less than 100 μg/ml.). This can further be diluted to other aqueous buffers.
Amino Acid Sequence Target protein is expressed with sequence (Thr20-Asn93) of Human hcc-1 (Uniprot #Q16627) fused with a polyhistidine tag at the C-terminus.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Chemokine (C-C motif) ligand 14 (CCL14) is a small cytokine belonging to the CC chemokine family. It is also commonly known as HCC-1. It is produced as a protein precursor that is processed to generate a mature active protein containing 74 amino acids that and is 46% identical in amino acid composition to CCL3 and CCL4. This chemokine is expressed in various tissues including spleen, bone marrow, liver, muscle, and gut. CCL14 activates monocytes, but does not induce their chemotaxis. Human CCL14 is located on chromosome 17 within a cluster of other chemokines belonging to the CC family.


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