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CBR4, human recombinant

Protein that plays role in mitochondrial fatty acid biosynthesis
Catalog #: P1156

In stock

$125.00

Product Details

Cat # +Size P1156-10
Size 10 μg
Alternate Name Carbonyl reductase family member 4, Quinone reductase CBR4, 3-oxoacyl-[acyl-carrier-protein] reductase
Gene Symbol CBR4
Gene ID 84869
Accession # Q8N4T8
Source E.coli
Appearance Liquid
Physical Form Description In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 5 mM DTT, 200 mM NaCl
Molecular Weight 27.5 kDa
Purity by SDS-PAGE > 95%
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MDKVCAVFGG SRGIGRAVAQ LMARKGYRLA VIARNLEGAK AAAGDLGGDH LAFSCDVAKE HDVQNTFEEM EKHLGRVNFL VNAAGINRDG LLVRTKTEDM VSQLHTNLLG SMLTCKAAMR TMIQQQGGSI VNVGSIVGLK GNSGQSVYSA SKGGLVGFSR ALAKEVARKK IRVNVVAPGF VHTDMTKDLK EEHLKKNIPL GRFGETIEVA HA
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

CBR4 belongs to the short-chain dehydrogenase/reductase family. The formation of heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity for o- and p-quinones. It plays a role in biosynthesis of fatty acids in mitochondria and has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro). Recombinant human CBR4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.


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