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A potent, ATP-competitive, D2-selective, p97 inhibitor
Catalog #: B1032
SKU-Size Size Price Qty
B1032-5 5 mg
B1032-25 25 mg
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Product Details

Alternate Name 1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide
Appearance White to off-white solid
CAS # 1542705-92-9
Molecular Formula C₂₄H₂₃N₅O₂
Molecular Weight 413.47
Purity ≥98% by HPLC
Solubility DMSO (>50 mg/ml)
InChi InChI=1S/C24H23N5O2/c1-15-12-18-17(22(25)30)8-5-9-21(18)29(15)24-27-20-10-11-31-14-19(20)23(28-24)26-13-16-6-3-2-4-7-16/h2-9,12H,10-11,13-14H2,1H3,(H2,25,30)(H,26,27,28)
PubChem CID 73051434
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


CB5083 is a potent, ATP-competitive, D2-selective, p97 inhibitor (IC₅₀ = 11 nM). In xenograft models, CB-5083 causes modulation of key p97-related pathways, induces apoptosis, and has antitumor activity in a broad range of both hematological and solid tumor models.

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