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CAY10685

An active clickable analog of the lysine acetyltransferase inhibitor CPTH2
Catalog #: B2842
SKU-Size Size Price Qty
B2842-1 1 mg
$65.00
B2842-5 5 mg
$225.00
More Sizes Get Quote

Product Details

Alternate Name 4-(4-chlorophenyl)-N-(cyclopentylideneamino)-N-prop-2-ynyl-1,3-thiazol-2-amine; 4-(4-chlorophenyl)-2-(2-cyclopentylidene-1-(prop-2-yn-1-yl)hydrazinyl)thiazole; Click Tag™ CAY10685
Appearance A crystalline solid
CAS # 1613116-16-7
Molecular Formula C₁₇H₁₆ClN₃S
Molecular Weight 329.85
Purity ≥95%
Solubility ~10 mg/ml in DMF
~3 mg/ml in Ethanol
~5 mg/ml in DMSO
SMILES C#CCN(C1=NC(=CS1)C2=CC=C(C=C2)Cl)N=C3CCCC3
InChi InChI=1S/C17H16ClN3S/c1-2-11-21(20-15-5-3-4-6-15)17-19-16(12-22-17)13-7-9-14(18)10-8-13/h1,7-10,12H,3-6,11H2
InChi Key JDLMHEOHMFFSDW-UHFFFAOYSA-N
PubChem CID 91971304
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

CAY10685 is an active clickable analog of the lysine acetyltransferase inhibitor 4-(4-chlorophenyl)-2-(2-cyclopentylidenehydrazinyl)thiazole (CPTH2 hydrochloride). The alkyne moiety reacts with an azide group upon copper exposure which tags the “clickable” molecules in cells. N-acetyltransferase 10 (NAT10) is a specific target of CAY10685. The inhibitor is used to study NAT10, it's role in nuclear architecture and for strategies to treat laminopathies and aging.


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