You have no items in your shopping cart.
Product Details
| Alternate Name | 3-(benzenesulfonyl)-1-(4-fluorophenyl)pyrrolo[3,2-b]quinoxalin-2-amine; 1-(4-Fluorophenyl)-3-(phenylsulfonyl)-1H-pyrrolo(2,3-B)quinoxalin-2-amine; SIRT1 Activator II |
|---|---|
| Appearance | A crystalline solid |
| CAS # | 374922-43-7 |
| Molecular Formula | C₂₂H₁₅FN₄O₂S |
| Molecular Weight | 418.4 |
| Purity | ≥95% |
| Solubility | ~20 mg/ml in DMSO and DMF |
| SMILES | C1=CC=C(C=C1)S(=O)(=O)C2=C(N(C3=NC4=CC=CC=C4N=C23)C5=CC=C(C=C5)F)N |
| InChi | InChI=1S/C22H15FN4O2S/c23-14-10-12-15(13-11-14)27-21(24)20(30(28,29)16-6-2-1-3-7-16)19-22(27)26-18-9-5-4-8-17(18)25-19/h1-13H,24H2 |
| InChi Key | CSFVFDHRYKBBPD-UHFFFAOYSA-N |
| PubChem CID | 1915791 |
| MDL Number | MFCD02236691 |
| Handling | Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure. |
| Storage Conditions | -20ºC |
| Shipping Conditions | RT |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
CAY10602 is an activator of SIRT1. The sirtuins (SIRTs) are NAD+-dependent histone deacetylases. SIRT1 alters gene expression by deacetylating transcription factors such as NF-κB, p53, and FOXO. CAY10602 suppresses the NF-κB-dependent induction of TNF-α by lipopolysaccharide in THP-1 cells at 20 μM and 60 μM. It is more potent as a suppressor of TNF-α release than resveratrol.
Why buy BioVision Products?
 |
 |
 |
 |
Innovation |
Affordability |
Global Presence |
Technical Support |
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways. |
BioVision is committed to providing the highest quality products at a competitive price. |
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery. |
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently. |
