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Cathepsin S Antibody

Catalog #: 3366R
SKU-Size Size Price Qty
3366R-30T 30 µg
$89.00
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Product Details

Antibody Target Cathepsin S
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding to amino acid 323 of human Cathepsin S
Accession # P25774
Gene ID 1520
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-cathepsin S polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human
Application Western blot, Immunohistochemistry
Positive Control Western Blot: Jurkat cell lysate. IHC: Lung tissue
Application & Usage Western blotting (0.5-4 µg/ml) and Immunohistochemistry (5 µg/ml). However, the optimal conditions should be determined individually. Detects 37 kDa human cathepsin S. Cross-reactivity to other species has not been determined.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cathepsin family of proteases contains several diverse classes of enzymes. The cysteine protease class comprises cathepsin B, H, K, L, O, and S. The aspartyl protease class contains cathepsin D and E. Cathepsin G belongs to the serine protease class. Cathepsins are involved in various cellular events such as peptide biosynthesis, protein degradation, and apoptosis. Cathepsin S has been shown to be present in aveloar macrophages.


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Wang N et al (2009) Immunol.; 183: 1542 - 1550.
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