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Cathepsin L Antibody

Polyclonal Antibody to detect Cathepsin L in human samples
Catalog #: 6669
SKU-Size Size Price Qty
6669-30T 30 μg
$89.00
6669-100 100 μg
$265.00
More Sizes Get Quote

Product Details

Antibody Target Cathepsin L
Alternate Name CTSL, CTSL1
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Recombinant human Cathepsin L protein (Cat # 1135)
Accession # P07711
Gene ID 1514
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
Purification Affinity Purified Antibody
Species Reactivity Human
Application Western blot
Positive Control Western Blot: Recombinant protein
Application & Usage Western blot: 1-4 µg/ml.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases.1-3 Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation.4-6 Although commonly recognized as a lysosomal protease, cathepsin L is also secreted. This broad-spectrum protease is potent in degrading several extracellular proteins (laminins, fibronectin, collagens I and IV, elastin, and other structural proteins of basement membranes) as well as serum proteins and cytoplasmic and nuclear proteins.


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