Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


Cathepsin L (Active), Human Liver

Plays a major role in intracellular protein catabolism
Catalog #: 7539

Product Details

Cat # +Size 7539-25
Size 25 µg
Alternate Name Cathepsin L1; Major Excreted Protein; CTSL; CTSL1
Gene ID 1514
Accession # P07711
Source Human liver
Appearance Sterile Filtered colorless solution
Physical Form Description Frozen
Molecular Weight 25 to 29 kDa
Formulation 20 mM malonate, pH 5.5, 1 mM EDTA, 400 mM NaCl
Specific Activity Greater than 1 unit per mg of protein, where one unit is defined as the amount of enzyme needed to hydrolyze one micromole of Z-Phe-Arg-AFC per minute at 25 C using 400 mM sodium acetate, pH 5.5. with 4 mM EDTA and 8 mM DTT as the activation buffer in the
Handling Centrifuge the vial prior to opening.
Storage Conditions -70 °C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not For Use in Humans.


Cathepsin L is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Substrates for Cathepsin L include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. Cathepsin L has been implicated in myofibril necrosis in some muscle diseases, and in the renal tubular response to proteinuira. Levels of Cathepsin L is a strong predictor of relapse and survival following primary breast tumor treatment. Recently, Cathepsin L has been shown to cleave the S1 subunit of the SARS-CoV-2 spike protein, which allows viral intry into the cell.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.