Cathepsin K, Active, human recombinant

Predominant proteinase responsible for the resorption of the bone matrix.
Catalog #: 7600 | abID: ab285940

Product Details

abID ab285940
Alternate Name CTSK, CTSO, CTSO3
Gene Symbol CTSK
Gene ID 1513
Accession # P43235
Source E. coli
Appearance Liquid
Physical Form Description 0.5 mg/ml solution in 25 mM Na2HPO4 and 500 mM NaCl (pH 7.0) with 50% glycerol.
Molecular Weight 23.5 kDa (115-329 aa)
Purity by SDS-PAGE ≥90%
Biological Activity The specific activity is >5000 mU/mg (1U = 1 μmole/min) as measured by Cathepsin K Activity Assay Kit (Catalog #K141-100)
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans


Cathepsin K, a member of the papain cysteine proteinase family is the predominant proteinase responsible for the resorption of the bone matrix. Cathepsin cleaves proteins such as collagen type I, collagen type II and osteonectin, thereby playing a role in bone remodeling and resorption in osteoporosis, osteolytic bone metastasis and rheumatoid arthritis (Bromme and Okamoto, 1995; Drake, F. et al 1996; Bossard et al, 1996).

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.