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Cathepsin G Inhibitor

A potent Cathepsin G inhibitor
Catalog #: 1982
$175.00

Product Details

Cat # +Size 1982-1
Size 1 mg
Appearance White solid
CAS # 429676-93-7
Molecular Formula C₃₆H₃₃N₂O₆P
Molecular Weight 620.63
Purity ≥98% by HPLC
Solubility DMSO
SMILES CN(C1CCN(CC1)C(=O)C2=CC=CC=C2)C(=O)C3=CC4=CC=CC=C4C=C3C(=O)C(C5=CC=CC6=CC=CC=C65)P(=O)(O)O
InChi InChI=1S/C36H33N2O6P/c1-37(28-18-20-38(21-19-28)35(40)25-11-3-2-4-12-25)36(41)32-23-27-14-6-5-13-26(27)22-31(32)33(39)34(45(42,43)44)30-17-9-15-24-10-7-8-16-29(24)30/h2-17,22-23,28,34H,18-21H2,1H3,(H2,42,43,44)
InChi Key GNOZQRKYZJSIPZ-UHFFFAOYSA-N
PubChem CID 9830518
MDL Number MFCD00130750
Handling Protect from light and mositure
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G (IC₅₀ = 53 nM and Ki = 63 nM). Acts as a weak inhibitor of chymotrypsin (Ki = 1.5 µM), thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase (IC₅₀ > 100 µM).


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