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Cathepsin D (active, human)

An active Lysosomal aspartyl protease
Catalog #: 1022
$175.00

Product Details

Cat # +Size 1022-5
Size 5 μg
Alternate Name Cathepsin D
Gene Symbol CTSB
Gene ID 1509
Accession # P07339
Source Human liver
Appearance Lyophilized
Physical Form Description Lyophilized from a solution containing 2 mM sodium phosphate, pH 6.5
Purity by SDS-PAGE ≥95%
Reconstitution Instructions Reconstitute the vial in H₂O to a concentration of 0.1-1 µg/µl. Aliquot and refreeze at -80°C immediately for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

Cathepsin D is an estrogen-regulated protein associated with tissue breakdown. Levels of cathepsin D have been positively correlated with recurring breast cancers of both node negative and node positive types. Additionally cathepsin D has been associated with amyloid formation in Alzheimer’s plaques. As cathepsin D activity is increased by cigarette smoke, the enzyme may contribute to lung tissue damage in smokers.


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