Product Details
| abID | ab91123 |
|---|---|
| Cat # +Size | 1022-5 |
| Size | 5 μg |
| Alternate Name | Cathepsin D |
| Gene Symbol | CTSB |
| Gene ID | 1509 |
| Accession # | P07339 |
| Source | Human liver |
| Appearance | Lyophilized |
| Physical Form Description | Lyophilized from a solution containing 2 mM sodium phosphate, pH 6.5 |
| Purity by SDS-PAGE | ≥95% |
| Reconstitution Instructions | Reconstitute the vial in H₂O to a concentration of 0.1-1 µg/µl. Aliquot and refreeze at -80°C immediately for future use. |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -80°C |
| Shipping Conditions | Dry Ice |
| USAGE | For Research Use Only! Not to be used in humans |
Details
Cathepsin D is an estrogen-regulated protein associated with tissue breakdown. Levels of cathepsin D have been positively correlated with recurring breast cancers of both node negative and node positive types. Additionally cathepsin D has been associated with amyloid formation in Alzheimer’s plaques. As cathepsin D activity is increased by cigarette smoke, the enzyme may contribute to lung tissue damage in smokers.
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