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Cathepsin B&L Inhibitor Z-Phe-Phe-FMK

based on 1 citations in multiple journalsCathepsin B&L Inhibitor Z-Phe-Phe-FMK14.1 4
A Cathepsin B & L inhibitor
Catalog #: 1126
$165.00

Product Details

Cat # +Size 1126-20C
Size 20 µl (10 mM)
Alternate Name Z-FF-FMK, Cathepsin B&L Inhibitor(fluoromethylketone)
Peptide Sequence Z-Phe-Phe-FMK
Appearance Liquid
Formulation DMSO (10 mM)
Molecular Formula C₂₇H₂₇FN₂O₄
Molecular Weight 462.5
Purity >95% by HPLC
SMILES C1=CC=C(C=C1)CC(C(=O)CF)NC(=O)C(CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3
InChi InChI=1S/C27H27FN2O4/c28-18-25(31)23(16-20-10-4-1-5-11-20)29-26(32)24(17-21-12-6-2-7-13-21)30-27(33)34-19-22-14-8-3-9-15-22/h1-15,23-24H,16-19H2,(H,29,32)(H,30,33)
InChi Key CAILNONEKASNSH-UHFFFAOYSA-N
PubChem CID 16760359
MDL Number MFCD03453604
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A potent, cell-permeable, and irreversible inhibitor of Cathepsin B and L.


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Lee et al., Long-term Incubation with Proteasome Inhibitors (PIs) Induces IDescription: {kappa}Bα Degradation via the Lysosomal Pathway in an IDescription: {kappa}B Kinase (IKK)-dependent and IKK-independent Manner. J. Biol. Chem., Nov 2013; 288: 32777 - 32786.
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