Product Details
| Cat # +Size | 6727-100 |
|---|---|
| Size | 100 μl |
| Antibody Target | Catalase |
| Alternate Name | CAT; Catalase |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | This CAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human CAT. |
| Accession # | P04040 |
| Gene ID | 847 |
| Appearance | Colorless liquid |
| Formulation | 100 µl of antibody in PBS with 0.09% (W/V) sodium azide |
| Purification | This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Species Reactivity | Human |
| Application | Western blot, IHC, FACS |
| Positive Control | Western blot: Mouse kidney tissue lysate, IHC: human lung carcinoma, FACS: 293 cells |
| Application & Usage | Western blot: ~1:1000, IHC: ~1:50–1:100, FACS: ~1:10-1:50. |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20 °C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Catalase is a peroxisome specific marker protein belonging to the catalase family. Defects in the gene encoding for the catalase protein can cause acatalasia, a disease characterized by the absence of catalase activity in red cells and associated with ulcerating oral lesions. Catalase is also an important regulator of oxidative stress and inflammation, and may contribute to the development of rheumatoid arthritis. Catalase, which can form a homotetramer, is found in all nearly all aerobically respiring organisms and functions in protecting cells from the toxic effects of hydrogen peroxide.
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