Caspase-9 Substrate LEHD-pNA

A caspase-9 substrate
Catalog #: 1076 | abID:

Product Details

Alternate Name Ac-LEHD-pNA, Caspase-9 Substrate, colorimetric, LEHD-pNA, LEHDPNA
Peptide Sequence Ac-Leu-Glu-His-Asp-pNA
Appearance Liquid
Formulation DMSO (4 mM)
Molecular Formula C₂₉H₃₈N₈O₁₁
Molecular Weight 674.7
Purity >98% by HPLC
SMILES CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC(=O)O)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)C
InChi InChI=1S/C29H38N8O11/c1-15(2)10-21(32-16(3)38)28(45)34-20(8-9-24(39)40)26(43)35-22(11-18-13-30-14-31-18)29(46)36-23(12-25(41)42)27(44)33-17-4-6-19(7-5-17)37(47)48/h4-7,13-15,20-23H,8-12H2,1-3H3,(H,30,31)(H,32,38)(H,33,44)(H,34,45)(H,35,43)(H,36,46)(H,39,40)(H,41,42)
InChi Key SHOGFKLEAOHMOJ-UHFFFAOYSA-N
PubChem CID 44135313
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Ready-to-use colorimetric substrate for caspase-9/Mch6 and related caspases that recognize the amino acid sequence LEHD. Caspase-9 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l= 400 nm) after cleavage from the peptide substrate LEHD-pNA, using a spectrophotometer or multi-well plate reader.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.
Lin et al., Furano-1,2-Naphthoquinone Inhibits Src and PI3K/Akt Signaling Pathways in Ca9-22 Human Oral Squamous Carcinoma Cells. Integr Cancer Ther, May 2014; 13: NP18 - NP28.
Yuan S et al (2008) FASEB J. 10.1096/FJ.08-107417.
Lee S-Y et al. (2007) Infect Immun. 75: 1291-1302.
Lieman, J.H., et al. (2005) J. Biol. Chem. 10.1074/jbc.M409371200.
Kawakami, M., et al. (2002) Mol. Cancer Thep. 1:999-1007.
For more citations of this product click here