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Caspase-6 Substrate VEID-pNA

based on 2 citations in multiple journalsCaspase-6 Substrate VEID-pNA24.1 4
A caspase-6 substrate
Catalog #: 1070
SKU-Size Size Price Qty
1070-200 200 assays
$255.00
1070-1000 1000 assays
$545.00
More Sizes Get Quote

Product Details

Alternate Name Ac-VEID-pNA, VEID-pNA, Caspase-6 Substrate, Colorimetric
Peptide Sequence Ac-Val-Glu-Ile-Asp-pNA
Appearance Liquid
Formulation DMSO (4 mM)
Molecular Formula C₂₈H₄₀N₆O₁₁
Molecular Weight 636.7
Purity >95% by HPLC
SMILES CCC(C)C(C(=O)NC(CC(=O)O)C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C
InChi InChI=1S/C28H40N6O11/c1-6-15(4)24(33-25(40)19(11-12-21(36)37)31-27(42)23(14(2)3)29-16(5)35)28(43)32-20(13-22(38)39)26(41)30-17-7-9-18(10-8-17)34(44)45/h7-10,14-15,19-20,23-24H,6,11-13H2,1-5H3,(H,29,35)(H,30,41)(H,31,42)(H,32,43)(H,33,40)(H,36,37)(H,38,39)
InChi Key VXTVKOWKXXPPNE-UHFFFAOYSA-N
PubChem CID 44135307
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Ready-to-use colorimetric substrate for caspase-6/Mch2 and related caspases that recognize the amino acid sequence VEID. Caspase-6 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l= 400 nm) after cleavage from the peptide substrate VEID-pNA, using a spectrophotometer or multi-well plate reader.


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Bai, S., et al. (2004) Am. Cancer Ther. 3:613-620.
Doostzadeh J., et al. (2000) J. Biol. Chem. 275:25336-25341.
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