Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Caspase-4 Inhibitor Z-LEVD-FMK

based on 6 citations in multiple journalsCaspase-4 Inhibitor Z-LEVD-FMK64.1 4
A caspase-4 inhibitor
Catalog #: 1108
SKU-Size Size Price Qty
1108-20C 20 µl (10 mM)
$125.00
1108-100 100 µl (2 mM)
$125.00
More Sizes Get Quote

Product Details

Alternate Name Z-LEVD-FMK, Caspase-4 Inhibitor (fluoromethylketone)
Peptide Sequence Z-Leu-Glu(OMe)-Val-Asp(OMe)-FMK
Appearance Liquid
Formulation 1108-100 In DMSO (2 mM); 1108-20C In DMSO (10 mM)
Molecular Formula C₃₁H₄₅FN₄O₁₀
Molecular Weight 652.7
Purity >95% by HPLC
SMILES CC(C)CC(C(=O)NC(CCC(=O)OC)C(=O)NC(C(C)C)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1
InChi InChI=1S/C31H45FN4O10/c1-18(2)14-23(35-31(43)46-17-20-10-8-7-9-11-20)29(41)33-21(12-13-25(38)44-5)28(40)36-27(19(3)4)30(42)34-22(24(37)16-32)15-26(39)45-6/h7-11,18-19,21-23,27H,12-17H2,1-6H3,(H,33,41)(H,34,42)(H,35,43)(H,36,40)
InChi Key WGJLXPZGHLANRB-UHFFFAOYSA-N
PubChem CID 44135220
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A synthetic peptide inhibitor that inhibits caspase-4 and related caspase activity. FMK inhibitors are irreversible and non-toxic, and can be used in both in vivo and in vitro studies. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.
Peng Yin, Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains. Acta Neuropathol., Feb. 2019;  30810811.
Akamatsu K et al (2009) Anticancer Res; 29: 2195-2204.
Jian CC et al (2009) Carcinogenesis; 30: 197 - 204.
Chen LH et al. (2008) Cancer Res. 68: 834 - 842.
Jiang CC et al. (2007) Cancer Res.67: 9750-9761.
For more citations of this product click here