Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Caspase-3 Substrate DEVD-pNA

based on 21 citations in multiple journalsCaspase-3 Substrate DEVD-pNA214.7 5
Caspase-3 substrate
Catalog #: 1008
SKU-Size Size Price Qty
1008-200 200 assays
$255.00
1008-1000 1000 assays
$545.00
More Sizes Get Quote

Product Details

Alternate Name Ac-DEVD-pNA, Caspase-3 Substrate, Colorimetric
Peptide Sequence Ac-Asp-Glu-Val-Asp-pNA
Appearance Liquid
Formulation In DMSO ( 4 mM)
Molecular Formula C₂₆H₃₄N₆O₁₃
Molecular Weight 638.58
Purity >98% by HPLC
SMILES CC(C)C(C(=O)NC(CC(=O)O)C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C
InChi InChI=1S/C26H34N6O13/c1-12(2)22(26(43)30-18(11-21(38)39)24(41)28-14-4-6-15(7-5-14)32(44)45)31-23(40)16(8-9-19(34)35)29-25(42)17(10-20(36)37)27-13(3)33/h4-7,12,16-18,22H,8-11H2,1-3H3,(H,27,33)(H,28,41)(H,29,42)(H,30,43)(H,31,40)(H,34,35)(H,36,37)(H,38,39)
InChi Key GGXRLUDNGFFUKI-UHFFFAOYSA-N
PubChem CID 4329
MDL Number MFCD00792707
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Ready-to-use colorimetric substrate for CPP32/caspase-3 and related caspases that recognize the amino acid sequence DEVD. The sequence DEVD is based on caspase-3 cleavage site in poly (ADP-ribose) polymerase (PARP). CPP32 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l = 400 nm) after cleavage from the peptide substrate DEVD-pNA, using a spectrophotometer or multi-well plate reader. The ready-to-use caspase substrate provides an economic alternative for researchers who perform large amounts of caspase assays.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.
Ya-Chi Lin, Oxaliplatin-Induced DHX9 Phosphorylation Promotes Oncogenic Circular RNA CCDC66 Expression and Development of Chemoresistance. Cancers (Basel)., Mar. 2020;  32187976.
Lin et al., Furano-1,2-Naphthoquinone Inhibits Src and PI3K/Akt Signaling Pathways in Ca9-22 Human Oral Squamous Carcinoma Cells. Integr Cancer Ther, May 2014; 13: NP18 - NP28.
Feinman, R. et al. HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury. Am J Physiol Gastrointest Liver Physiol, Oct 2010; 299: G833 - G843
Whitlock GC et al (2009) J. Med. Microbiol.; 58: 554 - 562.
Yuan S et al (2008) FASEB j. 10.1096/FJ.08-107417.
For more citations of this product click here