Caspase-3 Substrate DEVD-pNA

Caspase-3 substrate
Catalog #: 1008 | abID:

Product Details

Alternate Name Ac-DEVD-pNA, Caspase-3 Substrate, Colorimetric
Peptide Sequence Ac-Asp-Glu-Val-Asp-pNA
Appearance Liquid
Formulation In DMSO ( 4 mM)
Molecular Formula C₂₆H₃₄N₆O₁₃
Molecular Weight 638.58
Purity >98% by HPLC
SMILES CC(C)C(C(=O)NC(CC(=O)O)C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C
InChi InChI=1S/C26H34N6O13/c1-12(2)22(26(43)30-18(11-21(38)39)24(41)28-14-4-6-15(7-5-14)32(44)45)31-23(40)16(8-9-19(34)35)29-25(42)17(10-20(36)37)27-13(3)33/h4-7,12,16-18,22H,8-11H2,1-3H3,(H,27,33)(H,28,41)(H,29,42)(H,30,43)(H,31,40)(H,34,35)(H,36,37)(H,38,39)
PubChem CID 4329
MDL Number MFCD00792707
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Ready-to-use colorimetric substrate for CPP32/caspase-3 and related caspases that recognize the amino acid sequence DEVD. The sequence DEVD is based on caspase-3 cleavage site in poly (ADP-ribose) polymerase (PARP). CPP32 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l = 400 nm) after cleavage from the peptide substrate DEVD-pNA, using a spectrophotometer or multi-well plate reader. The ready-to-use caspase substrate provides an economic alternative for researchers who perform large amounts of caspase assays.

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Ya-Chi Lin, Oxaliplatin-Induced DHX9 Phosphorylation Promotes Oncogenic Circular RNA CCDC66 Expression and Development of Chemoresistance. Cancers (Basel)., Mar. 2020;  32187976.
Lin et al., Furano-1,2-Naphthoquinone Inhibits Src and PI3K/Akt Signaling Pathways in Ca9-22 Human Oral Squamous Carcinoma Cells. Integr Cancer Ther, May 2014; 13: NP18 - NP28.
Feinman, R. et al. HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury. Am J Physiol Gastrointest Liver Physiol, Oct 2010; 299: G833 - G843
Whitlock GC et al (2009) J. Med. Microbiol.; 58: 554 - 562.
Yuan S et al (2008) FASEB j. 10.1096/FJ.08-107417.
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