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Caspase-3 Inhibitor Q-DEVD-OPh

A caspase-3 inhibitor
Catalog #: 1175
SKU-Size Size Price Qty
1175-1 1 mg
1175-3 3 mg
1175-5 5 mg
More Sizes Get Quote

Product Details

Alternate Name Q-DEVD-Oph, Q-Asp-Glu-Val-Asp-Oph
Peptide Sequence Quinolyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-OPh
Appearance Off-white solid
Molecular Formula C₃₈H₄₃F₂N₅O₁₂
Molecular Weight 799.77
Purity >90% by HPLC
Solubility DMSO
InChi InChI=1S/C38H43F2N5O12/c1-20(2)33(38(53)43-27(17-31(48)55-4)29(46)19-57-34-22(39)10-8-11-23(34)40)45-36(51)26(15-16-30(47)54-3)42-37(52)28(18-32(49)56-5)44-35(50)25-14-13-21-9-6-7-12-24(21)41-25/h6-14,20,26-28,33H,15-19H2,1-5H3,(H,42,52)(H,43,53)(H,44,50)(H,45,51)
PubChem CID 44135278
Handling Protect from moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A second-generation capase-3 inhibitor that is potent, cell permeable, irreversible and nontoxic.

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Lei Hu, Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate. Cell Death Dis., Apr. 2020;  32332857.
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