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Caspase-3/7 Inhibitor

A specific caspase-3/7 inhibitor
Catalog #: 2780
SKU-Size Size Price Qty
2780-1 1 mg
2780-5 5 mg
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Product Details

Alternate Name 5-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]sulfonyl-1H-indole-2,3-dione
Appearance Yellow solid
CAS # 220509-74-0
Molecular Formula C₁₄H₁₆N₂O₅S
Molecular Weight 324.4
Purity ≥97% by HPLC
Solubility DMSO (~ 200 mg/ml)
InChi InChI=1S/C14H16N2O5S/c1-21-8-9-3-2-6-16(9)22(19,20)10-4-5-12-11(7-10)13(17)14(18)15-12/h4-5,7,9H,2-3,6,8H2,1H3,(H,15,17,18)/t9-/m0/s1
PubChem CID 9840223
MDL Number MFCD22581511
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Caspase-3/7 inhibitor is a potent, cell-permeable, specific, and reversible inhibitor of caspase-3 (Ki = 60 nM) and caspase-7 (Ki = 170 nM). It acts as a weaker inhibitor of caspase-9 (Ki = 3.1 µM).

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