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Caspase-10 Substrate AEVD-pNA

based on 2 citations in multiple journalsCaspase-10 Substrate AEVD-pNA24.1 4
A caspase-10 substrate
Catalog #: 1114

In stock

SKU-Size Size Price Qty
1114-200 200 assays
$255.00
1114-1000 1000 assays
$565.00
More Sizes Get Quote

Product Details

Alternate Name Ac-AEVD-pNA, Caspase-10 Substrate, Colorimetric
Peptide Sequence Ac-Ala-Glu-Val-Asp-pNA
Appearance Liquid
Formulation DMSO (4 mM)
Molecular Formula C₂₅H₃₄N₆O₁₁
Molecular Weight 594.7
Purity >99% by HPLC
SMILES CC(C)C(C(=O)NC(CC(=O)O)C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C
InChi InChI=1S/C25H34N6O11/c1-12(2)21(30-23(38)17(9-10-19(33)34)28-22(37)13(3)26-14(4)32)25(40)29-18(11-20(35)36)24(39)27-15-5-7-16(8-6-15)31(41)42/h5-8,12-13,17-18,21H,9-11H2,1-4H3,(H,26,32)(H,27,39)(H,28,37)(H,29,40)(H,30,38)(H,33,34)(H,35,36)
InChi Key BKZWKAJKSQIGBP-UHFFFAOYSA-N
PubChem CID 44135310
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Ready-to-use colorimetric substrate for caspases that recognize the amino acid sequence AEVD. Caspase activity can be quantified by spectrophotometric detection of free pNA (l = 400 nm) after cleaved from the peptide substrate AEVD-pNA, using a spectrophotometer or multi-well plate reader. The ready-to-use caspase substrate provides an economical alternative for researchers who perform large volume of caspase assays.


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Bian, Y. et al. Neuregulin-1 Attenuated Doxorubicin-Induced Decrease in Cardiac Troponins. Am. J. Physiol. Heart Circ. Physiol. 2009; 297: H1974-H1983.
Doostzadeh J., et al. (2000) J. Biol. Chem. 275:25336-25341.
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