Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Caspase-1 Substrate YVAD-pNA

based on 2 citations in multiple journalsCaspase-1 Substrate YVAD-pNA24.1 4
A caspase-1 substrate
Catalog #: 1104
SKU-Size Size Price Qty
1104-200 200 assays
$255.00
1104-1000 1000 assays
$545.00
More Sizes Get Quote

Product Details

Alternate Name Ac-YVAD-pNA, Caspase-1 Substrate, Colorimetric
Peptide Sequence Ac-Tyr-Val-Ala-Asp-pNA
Appearance Liquid
Formulation DMSO (4 mM)
Molecular Formula C₂₉H₃₆N₅O₁₀
Molecular Weight 628.6
Purity >98% by HPLC
SMILES CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C
InChi InChI=1S/C29H36N6O10/c1-15(2)25(34-28(42)22(31-17(4)36)13-18-5-11-21(37)12-6-18)29(43)30-16(3)26(40)33-23(14-24(38)39)27(41)32-19-7-9-20(10-8-19)35(44)45/h5-12,15-16,22-23,25,37H,13-14H2,1-4H3,(H,30,43)(H,31,36)(H,32,41)(H,33,40)(H,34,42)(H,38,39)/t16-,22-,23-,25-/m0/s1
InChi Key YDPNOCSPPGFBPX-XNHCRPTKSA-N
PubChem CID 10484117
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Ready-to-use colorimetric substrate for caspase-1/ICE and related caspases that recognize the amino acid sequence YVAD. Caspase-1 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l= 400 nm) after cleavage from the peptide substrate YVAD-pNA, using a spectrophotometer or multi-well plate reader. The ready-to-use caspase substrate provides an economic alternative for large volume users.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.
Oh, H. A. et. al. Distinct Effects of Imperatorin on Allergic Rhinitis: Imperatorin Inhibits Caspase-1 Activity In Vivo and In Vitro. J. Pharmacol. Exp. Ther., Oct 2011; 339: 72 - 81.
Doostzadeh J., et al. (2000) J. Biol. Chem. 275:25336-25341.
For more citations of this product click here