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Carglumic acid

An activator of carbamoyl phosphate synthetase 1 (CPS1)
Catalog #: B2447
SKU-Size Size Price Qty
B2447-10 10 mg
B2447-50 50 mg
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Product Details

Alternate Name N-(aminocarbonyl)-L-glutamic acid, N-Carbamyl-L-Glutamic Acid
Appearance White to off-white solid
CAS # 1188-38-1
Molecular Formula C₆H₁₀N₂O₅
Molecular Weight 190.15
Purity ≥98%
Solubility ~30 mg/ml in DMSO
InChi InChI=1S/C6H10N2O5/c7-6(13)8-3(5(11)12)1-2-4(9)10/h3H,1-2H2,(H,9,10)(H,11,12)(H3,7,8,13)/t3-/m0/s1
PubChem CID 121396
MDL Number MFCD00047874
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Carglumic acid is an activator of carbamoyl phosphate synthetase 1 (CPS1), the first enzyme in the urea cycle that is responsible for removal and detoxification of ammonia, making this drug a valuable agent for therapy of hyperammonemia caused by rare forms of urea cycle defects.

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