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Product Details
| Alternate Name | (S)-4-methyl-N-((S)-1-((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide; PR-171 |
|---|---|
| Appearance | Crystalline solid |
| CAS # | 868540-17-4 |
| Molecular Formula | C₄₀H₅₇N₅O₇ |
| Molecular Weight | 719.91 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (~50 mg/ml) |
| SMILES | CC(C)CC(C(=O)C1(CO1)C)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(C)C)NC(=O)C(CCC3=CC=CC=C3)NC(=O)CN4CCOCC4 |
| InChi | InChI=1S/C40H57N5O7/c1-27(2)22-32(36(47)40(5)26-52-40)42-39(50)34(24-30-14-10-7-11-15-30)44-38(49)33(23-28(3)4)43-37(48)31(17-16-29-12-8-6-9-13-29)41-35(46)25-45-18-20-51-21-19-45/h6-15,27-28,31-34H,16-26H2,1-5H3,(H,41,46)(H,42,50)(H,43,48)(H,44,49)/t31-,32-,33-,34-,40+/m0/s1 |
| InChi Key | BLMPQMFVWMYDKT-NZTKNTHTSA-N |
| PubChem CID | 11556711 |
| Handling | Protect from light and moisture |
| Storage Conditions | -20 ̊C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Carfilzomib (PR-171) is a next generation, irreversible and selective inhibitor of the chymotrypsin-like activity of the proteasome. It displays potent antineoplastic activity.
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