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Carbonic Anhydrase XIV/CA14, Human Recombinant

Zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide.
Catalog #: P1582
SKU-Size Size Price Qty
P1582-20 20 μg
$115.00
P1582-100 100 μg
$455.00
More Sizes Get Quote

Product Details

Alternate Name Carbonic anhydrase 14, CAXiV
Gene Symbol CA14
Gene ID 23632
Accession # Q9ULX7
Source E. coli
Appearance Liquid
Physical Form Description In 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 mM DTT
Molecular Weight 33.2 kDa (298aa) (N terminus His-Tag)
Purity by SDS-PAGE >85%
Amino Acid Sequence aa 16-290
Handling Centrifuge the vial prior to opening.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA14 is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. Recombinant human CA14 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.


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