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Carbamazepine

Inhibitor of neuronal NaV channels
Catalog #: B2401

In stock

SKU-Size Size Price Qty
B2401-50 50 mg
$75.00
B2401-250 250 mg
$195.00
More Sizes Get Quote

Product Details

Alternate Name 5H-Dibenz[b,f]azepine-5-carboxamide, CBZ
Appearance White solid
CAS # 298-46-4
Molecular Formula C₁₅H₁₂N₂O
Molecular Weight 236.27
Purity ≥98% by HPLC
Solubility >20 mg/ml in DMSO
SMILES C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)N
InChi InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)
InChi Key FFGPTBGBLSHEPO-UHFFFAOYSA-N
PubChem CID 2554
MDL Number MFCD00005073
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Carbamazepine is an inhibitor of neuronal voltage-gated Na+ channels. It displays anticonvulsant activity and potentiates GABA-induced Cl- currents in HEK 293 cells expressing the GABAA receptor α1β2γ2 subtype combination. Can induce autophagy by inhibiting inositol synthesis. Also acts as an in vitro inducer of CYP3A4, the main human metabolizing enzyme present in the liver and intestine.


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