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Captopril

An angiotensin-converting enzyme (ACE) inhibitor
Catalog #: B1187
SKU-Size Size Price Qty
B1187-1G 1 g
$75.00
B1187-5G 5 g
$245.00
More Sizes Get Quote

Product Details

Alternate Name (2S)-1-(3-Mercapto-2-methyl-propionyl)-L-proline
Appearance White solid
CAS # 62571-86-2
Molecular Formula C₉H₁₅NO₃S
Molecular Weight 217.28
Purity ≥98% by HPLC
Solubility DMSO (20 mg/ml)
SMILES CC(CS)C(=O)N1CCCC1C(=O)O
InChi InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1
InChi Key FAKRSMQSSFJEIM-RQJHMYQMSA-N
PubChem CID 44093
MDL Number MFCD00168073
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Captopril is an angiotensin-converting enzyme (ACE) inhibitor (IC₅₀ = 0.022 μM). Also inhibits the bifunctional Zn2+-containing leukotriene A4 hydrolase/aminopeptidase (LTA4 hydrolase) reversibly and competitively (Ki = 6.0 μM for leukotriene B4> formation and Ki = 60 nM for L-lysine-p-nitroanilide). Displays vasodilatory and antihypertensive effects in vivo. Clinically useful antihypertensive agent.


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