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Calpain Inhibitor Z-LLY-FMK

based on 2 citations in multiple journalsCalpain Inhibitor Z-LLY-FMK24.1 4
A cathepsin B & L and Calpain inhibitor
Catalog #: 1125

Product Details

Cat # +Size 1125-20C
Size 20 µl (10 mM)
Alternate Name Z-LLY-FMK, Calpain Inhibitor(fluoromethylketone)
Peptide Sequence Z-Leu-Leu-Tyr-FMK
Appearance Liquid
Formulation DMSO (10 mM)
CAS # 133410-84-1
Molecular Formula C₃₀H₄₀FN₃O₆
Molecular Weight 557.7
Purity >95% by HPLC
InChi InChI=1S/C30H40FN3O6/c1-19(2)14-25(28(37)32-24(27(36)17-31)16-21-10-12-23(35)13-11-21)33-29(38)26(15-20(3)4)34-30(39)40-18-22-8-6-5-7-9-22/h5-13,19-20,24-26,35H,14-18H2,1-4H3,(H,32,37)(H,33,38)(H,34,39)
PubChem CID 16760337
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A potent, cell-permeable, and irreversible inhibitor of calpain II (k₂ = 28,900 M⁻¹s⁻¹). Also acts as an inhibitor of cathepsin L (k₂= 680,000 M⁻¹s⁻¹).

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Calle Y. et al. (2006) J. Cell Sci. 119: 2375-2385
Li, J. H. and Pober, J. S. (2005) J. Immunol. 175: 1858-1866.
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