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Calpain-2 Antibody

Catalog #: 3372
SKU-Size Size Price Qty
3372-30T 30 µl
$89.00
3372-100 100 µl
$280.00
More Sizes Get Quote

Product Details

Antibody Target Calpain 2
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide mapping to the C-terminus of the domain III of human Calpain 2 large subunit
Accession # NP_001739
Gene ID 824
Appearance Colorless liquid
Formulation 100 µl affinity purified rabbit polyclonal anti-calpain 2 antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot
Application & Usage Western blotting (1:200-1000 dilutions). However, the optimal concentrations should be determined individually. The anti-calpain 2 antibody recognizes the 80 kDa Calpain 2. It does not cross-react with other calpains
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Calpains are cytosolic, calcium-dependent, cysteine proteases that are ubiquitously expressed in mammalian and avian tissues. Calpain-1 and 2 consist of a common small subunit and a large variable subunit. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF-hand domain IV. Type I calpain requires micromolar amounts of calcium, while type II calpain requires millimolar amounts of calcium.


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