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Calcitonin, Human (Synthetic peptide)

Peptide hormone that inhibits the activity of osteoclasts, first messenger to regulate adenylyl cyclase/cAMP
Catalog #: P1433
SKU-Size Size Price Qty
P1433-1 1 mg
$125.00
P1433-5 5 mg
$575.00
More Sizes Get Quote

Product Details

Alternate Name Calcitonin carboxyl-terminal peptide, CCP, PDN-21, CALCA, CALC1, Katacalcin
Gene Symbol CALCA
Gene ID 796
Accession # P01258
Source Synthetic peptide
Appearance Lyophilized powder
Physical Form Description Lyophilized
Molecular Weight 3.42 KDa
Purity by SDS-PAGE >95%
Reconstitution Instructions Reconstitute in sterile deionized water. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
Amino Acid Sequence aa, 85-116
Handling Centrifuge the vial prior to opening.
Storage Conditions RT
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Calcitonin is a peptide hormone with 32 amino acids and mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, an N terminal residue, calcitonin and katacalcin. Calcitonin is also found in fish, reptiles, birds and other mammals. Calcitonin opposes the action of the parathyroid hormone (PTH), helping to regulate the blood’s calcium and phosphate levels. Calcitonin also acts as a first messenger to regulate adenylyl cyclase/cAMP and mammalian sperm function.


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