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A non-selective inhibitor of calcium-activated chloride channels (CaCCs)
Catalog #: B2014

In stock

SKU-Size Size Price Qty
B2014-5 5 mg
B2014-25 25 mg
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Product Details

Alternate Name 6-(1,1-dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid; TMEM16-Blocker I
Appearance Crystalline solid
CAS # 407587-33-1
Molecular Formula C₁₈H₂₁NO₄S
Molecular Weight 347.43
Purity ≥98% by HPLC
Solubility DMSO (>30 mg/ml)
InChi InChI=1S/C18H21NO4S/c1-18(2,3)10-6-7-11-13(9-10)24-16(14(11)17(21)22)19-15(20)12-5-4-8-23-12/h4-5,8,10H,6-7,9H2,1-3H3,(H,19,20)(H,21,22)
PubChem CID 2898877
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


CaCCinh-A01 is a TMEM16 Blocker. It is a non-selective inhibitor of calcium-activated chloride channels (CaCCs) that blocks ATP-stimulated chloride conductance in human salivary gland, intestinal, and bronchial epithelium (mean IC₅₀ = 10 µM).

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