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C-reactive/CRP Monoclonal Antibody

Monoclonal antibody to detect CRP in human samples.
Catalog #: A1208
$265.00

Product Details

Cat # +Size A1208-100
Size 100 µg
Antibody Target CRP
Alternate Name CRP, PTX1, C-reactive protein
Host Rabbit
Antibody Type Monoclonal
Isotype Rabbit IgG
Immunogen Human CRP Protein
Accession # P02741
Gene ID 1401
Appearance Colorless liquid
Formulation In NaCl with 15 mM NaN3 (pH 7.4)
Purification Protein G purified
Species Reactivity Human
Application ELISA, LEITA, LFIA
Positive Control LETIA: CRP protein, blood samples
Application & Usage WB; 1:500 – 1:2000
Handling The antibody solution should be gently mixed before use
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

C-reactive protein (CRP) is an annular (ring-shaped), pentameric protein found in blood plasma, the levels of which rise in response to inflammation (i.e., C-reactive protein is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion from macrophages and T cells). Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system via the C1Q complex. CRP is synthesized by the liver in response to factors released by macrophages and fat cells (adipocytes).It is a member of the pentraxin family of proteins. It is not related to C-peptide (insulin) or protein C (blood coagulation). C-reactive protein was the first pattern recognition receptor (PRR) to be identified.


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