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Product Details
| Cat # +Size | A1208-100 |
|---|---|
| Size | 100 µg |
| Antibody Target | CRP |
| Alternate Name | CRP, PTX1, C-reactive protein |
| Host | Rabbit |
| Antibody Type | Monoclonal |
| Isotype | Rabbit IgG |
| Immunogen | Human CRP Protein |
| Accession # | P02741 |
| Gene ID | 1401 |
| Appearance | Colorless liquid |
| Formulation | In NaCl with 15 mM NaN3 (pH 7.4) |
| Purification | Protein G purified |
| Species Reactivity | Human |
| Application | ELISA, LEITA, LFIA |
| Positive Control | LETIA: CRP protein, blood samples |
| Application & Usage | WB; 1:500 – 1:2000 |
| Handling | The antibody solution should be gently mixed before use |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not to be used in humans |
Details
C-reactive protein (CRP) is an annular (ring-shaped), pentameric protein found in blood plasma, the levels of which rise in response to inflammation (i.e., C-reactive protein is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion from macrophages and T cells). Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system via the C1Q complex. CRP is synthesized by the liver in response to factors released by macrophages and fat cells (adipocytes).It is a member of the pentraxin family of proteins. It is not related to C-peptide (insulin) or protein C (blood coagulation). C-reactive protein was the first pattern recognition receptor (PRR) to be identified.
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