Product Details
| Cat # +Size | E4701-100 |
|---|---|
| Size | 96 assays |
| Kit Summary | • Detection method- Absorbance (450 nm) • Species reactivity- Human • Application- quantitative measurement of c-peptides in serum samples. |
| Detection Method | Absorbance-450 nm |
| Species Reactivity | Human |
| Features & Benefits | Detection of C-peptides in human serum samples. |
| Kit Components | • Stop Solution • Wash Solution 20X • TMB Solution • Microwells coated with anti-C-peptide Ab • Enzyme Conjugate (Ready to use) • Standards (1-6) 6 vials • lyophylized |
| Storage Conditions | 2-8°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
C-peptide serves as an important linker between A-chain and B-chain of insulin and facilitates the efficient assembly, folding, and processing of insulin in the endoplasmic reticulum. Equimolar amounts of C-peptide and insulin are stored in secretory granules of the pancreatic beta cells and both are eventually released to the portal circulation. The sole interest in C-peptide was as a marker of insulin secretion. Newly diagnosed diabetes patients often get their C-peptide levels measured as a means of distinguishing type 1 and type 2 diabetes. C-peptide is also used for determining the possibility of gastrinomas associated with Multiple Endocrine Neoplasm syndromes (MEN 1).
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