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C-Kit/CD117 Antibody (NT)

Polyclonal Antibody to detect c-kit/CD117 in human samples.
Catalog #: 6777

Product Details

Cat # +Size 6777-100
Size 100 μl
Antibody Target c-Kit/CD117
Alternate Name KIT, Mast/stem cell growth factor receptor, Proto-oncogene tyrosine-protein kinase Kit
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen This c-KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-40 amino acids from the N-terminal region of human c-KIT.
Accession # 3815
Gene ID P10721
Appearance Colorless liquid
Formulation 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Species Reactivity Human.
Application Western blot, IHC, IF.
Positive Control Western blot: HeLa cell lysate, IHC: Breast carcinoma, FACS: Hela cells.
Application & Usage WB: 1:1000, IHC: 1:10 – 1:50, IF: 1:10 – 1:50.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis, and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.

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