Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

C-Kit/CD117 Antibody (NT)

Polyclonal Antibody to detect c-kit/CD117 in human samples.
Catalog #: 6777
$245.00

Product Details

Cat # +Size 6777-100
Size 100 μl
Antibody Target c-Kit/CD117
Alternate Name KIT, Mast/stem cell growth factor receptor, Proto-oncogene tyrosine-protein kinase Kit
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen This c-KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-40 amino acids from the N-terminal region of human c-KIT.
Accession # 3815
Gene ID P10721
Appearance Colorless liquid
Formulation 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Species Reactivity Human.
Application Western blot, IHC, IF.
Positive Control Western blot: HeLa cell lysate, IHC: Breast carcinoma, FACS: Hela cells.
Application & Usage WB: 1:1000, IHC: 1:10 – 1:50, IF: 1:10 – 1:50.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis, and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.