Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Butyrolactone 3

An inhibitor of histone acetyltransferase Gcn5
Catalog #: B2817
SKU-Size Size Price Qty
B2817-1 1 mg
B2817-5 5 mg
More Sizes Get Quote

Product Details

Alternate Name rel-tetrahydro-4-methylene-5-oxo-2R-propyl-3S-furancarboxylic acid
Appearance Crystalline solid
CAS # 778649-18-6
Molecular Formula C₉H₁₂O₄
Molecular Weight 184.19
Purity ≥95%
Solubility ~2 mg/ml in PBS, pH 7.2
~14 mg/ml in ethanol and DMSO
InChi InChI=1S/C9H12O4/c1-3-4-6-7(8(10)11)5(2)9(12)13-6/h6-7H,2-4H2,1H3,(H,10,11)/t6-,7+/m0/s1
PubChem CID 10081070
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


Butyrolactone 3 is an inhibitor of histone acetyltransferase (HAT) Gcn5. Gcn5 acetylates histones H2B and H3. Butyrolactone 3 inhibits Gcn5 with an IC₅₀ value of 100 μM. It has an affinity to the Gcn5 enzyme similar to its substrate, histone H3. It inhibits pre-mRNA splicing with an IC₅₀ of 0.5 mM.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.