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Anti-BTLA Antibody

Polyclonal antibody to detect BTLA/CD272 in human samples.
Catalog #: A1082
$295.00

Product Details

Cat # +Size A1082-50
Size 50 µg
Antibody Target BTLA
Alternate Name BTLA, CD272
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Accession # Q7Z6A9
Gene ID 151888
Appearance Colorless liquid
Formulation PBS with 0.09% (W/V) sodium azide. 
Purification Protein A column, followed by peptide affinity purification.
Species Reactivity Human
Application IHC, IF, WB
Positive Control WB: Jurkat cell lysate; IHC: human intestine tissue; IF; human instetine tissue
Application & Usage WB: 1-2 µg/ml; IHC: 2.5 µg/ml; IF: 20 µg/ml
Handling The antibody solution should be gently mixed before use
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain. Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells. Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis


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