Bryostatin 1

A protein kinase C (PKC) activator
Catalog #: 2513 | abID:

Product Details

Cat # +Size 2513-10
Size 10 µg
Alternate Name (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[,7.111,15]nonacos-8-en-12-yl 2,4-octadienoic acid ester; NSC 339555
Appearance White lyophilized solid
CAS # 83314-01-6
Molecular Formula C₄₇H₆₈O₁₇
Molecular Weight 905.04
Purity ≥98%
Solubility 25 or 25 mg/ml in DMSO
InChi InChI=1S/C47H68O17/c1-10-11-12-13-14-15-39(51)62-43-31(22-41(53)58-9)21-34-25-37(28(2)48)61-42(54)24-32(50)23-35-26-38(59-29 (3)49)45(6,7)46(55,63-35)27-36-19-30(20-40(52)57-8)18-33(60-36)16-17-44(4,5)47(43,56) 64-34/h12-17,20,22,28,32-38,43,48,50,55-56H,10-11,18-19,21,23-27H2,1-9H3/b13-12+,15-14+, 17-16+,30-20+,31-22+/t28-,32-,33+,34+,35-,36+,37-,38+,43+,46+,47-/m1/s1
PubChem CID 5280757
MDL Number MFCD00893832
Handling Protect from air and moisture
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Bryostatin 1 is a naturally occurring macrocyclic lactone that binds to and activates protein kinase C, but its biological effects differ greatly from those induced by other protein kinase C activators. More potent than phorbol myristate acetate for translocating PKCδ and ε.

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