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Bryostatin 1

A protein kinase C (PKC) activator
Catalog #: 2513

In stock

SKU-Size Size Price Qty
2513-10 10 µg
$135.00
2513-50 50 µg
$495.00
More Sizes Get Quote

Product Details

Alternate Name NSC 339555; (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl 2,4-octadienoic acid ester
Appearance White lyophilized solid
CAS # 83314-01-6
Molecular Formula C₄₇H₆₈O₁₇
Molecular Weight 905.04
Purity ≥98%
Solubility DMSO (25 mg/ml) or EtOH (25 mg/ml)
SMILES CCCC=CC=CC(=O)OC1C(=CC(=O)OC)CC2CC(OC(=O)CC(CC3CC(C(C(O3)(CC4CC(=CC(=O)OC)CC(O4)C=CC(C1(O2)O)(C)C)O)(C)C)OC(=O)C)O)C(C)O
InChi InChI=1S/C47H68O17/c1-10-11-12-13-14-15-39(51)62-43-31(22-41(53)58-9)21-34-25-37(28(2)48)61-42(54)24-32(50)23-35-26-38(59-29(3)49)45(6,7)46(55,63-35)27-36-19-30(20-40(52)57-8)18-33(60-36)16-17-44(4,5)47(43,56)64-34/h12-17,20,22,28,32-38,43,48,50,55-56H,10-11,18-19,21,23-27H2,1-9H3/b13-12+,15-14+,17-16+,30-20+,31-22+/t28-,32-,33+,34+,35-,36+,37-,38+,43+,46+,47-/m1/s1
InChi Key MJQUEDHRCUIRLF-TVIXENOKSA-N
PubChem CID 5280757
MDL Number MFCD00893832
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Bryostatin 1 is a naturally occurring macrocyclic lactone that binds to and activates protein kinase C, but its biological effects differ greatly from those induced by other protein kinase C activators. More potent than phorbol myristate acetate for translocating PKCδ and ε.


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